Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep874 | Thyroid cancer | ECE2015

Differentiated thyroid cancer: tendency changes from 1970 to 2012 in the southwest of Spain

Ortega Antonio Jesus Martinez , Gonzalez Elena Navarro , Vazquez Raquel Guerrero , de los Reyes Romero Lluch Ana , Martos Jose Manuel , Cuenca Ignacio Cuenca

There is a specific unit specialised in treating differentiated thyroid cancer (DTC) at the Endocrinology Department from a hospital the southwest of Spain that attends patients from two different provinces. Owing to environmental pollution, one of them has higher incidence of cancer.To evaluate the changes in the clinical presentation of DTC over time and analyse possible differences between patients from the two provinces, we designed a descriptive ret...

ea0099p302 | Endocrine-Related Cancer | ECE2024

Alteration in the molecular components of machinery that regulate gene expression mechanisms and genomic stability in thyroid cancer and their association with tumour behaviour and/or clinical features

Martinez Vara Andrea , Pastrana Francisco Porcel , Di-Caro Isidoro , Sarmento-Cabral Andre , Sanchez Sanchez Rafael , Lluch Ana Romero , Santisteban Pilar , Gonzalez Elena Navarro , Moreno Maria A Gavez , Luque Raul M , Fuentes Antonio J Martinez

Emerging evidence indicates that the cellular machineries controlling gene expression mechanisms and genomic stability are altered in several endocrine-related cancers (ERCs), leading to some oncogenic events associated with tumour progression/aggressiveness. However, whether this phenomenon also occurs in thyroid cancer has not been yet explored. Therefore, this study was focused on: 1) investigating the potential alteration in the levels of components of the molecular machin...